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The core of its biological activity lies in its role as a precursor to GSH, the primary intracellular antioxidant

Mitochondria represent the dominant ATP source in PACs and are strategically positioned around granule-rich domains, where they respond to local Ca 2+ elevations and provide energy for exocytosis ( 2+ buffers that limit the spread of Ca 2+ signals and support apicalbasal polarity during stimulussecretion coupling

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Many metabolic disorders can lead to endpoints such as impaired methylation, sulfuration, and detoxification pathways and nutritional deficiencies

Authors are given an opportunity to expand on the circumstances, limitations etc