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Compared to the intracellular phagosomal space where the substrate availability is controlled, the MPO-dependent oxidative biochemistry in the extracellular environment is usually far more diverse, leading to substantial modifications of a wide variety of biomolecules, including DNA, lipids, carbohydrates and proteins

Glucagon receptor activation increases energy expenditure and hepatic lipid metabolism, meaning your body burns more calories at rest and processes stored fat in the liver more efficiently

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