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Description

A general and efficient Suzuki-Miyaura cross-coupling protocol using weak base and no water: the essential role of acetate

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If high-concentration sulfuric acid is introduced directly, calcium ions present in the water will react with sulfate ions to form calcium sulfate precipitates

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By blocking NNMT, it prevents the methylation and degradation of nicotinamide, increasing the substrate available for NAD+ synthesis

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