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Leaky Gut Lab Test Hormone tests making it challenging to pinpointLeaky Gut Test At Home Stool Test for Intestinal Permeability The Leaky Gut Test measures zonulin levels, a protein that regulates the permeability of the intestines. Elevated zonulin levels are associated with intestinal permeability, commonly referred to as leaky gut syndrome. This condition occurs when the intestinal barrier becomes compromised, allowing particles such as undigested food, toxins, and microbes to pass into the bloodstream,