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For example, the availability of nutrients in the TME affects the metabolic status of cancer and stromal cells, while many metabolites, such as lactate, secreted by cancer cells further promote the formation of an immunosuppressive microenvironment

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doi:10.1056/NEJM196306132682401

Henderickx JGE, de Weerd H, Groot Jebbink LJ, van Zoeren-Grobben D, Hemels MAC, van Lingen RA, et al

Vitamin C (Ascorbic Acid) Other Names: Ascorbic Acid Uses & Benefits: Antioxidant, supports immune function, collagen synthesis, and enhances iron absorption