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In addition, hypoxia also promotes the formation of tumor neovascularization, enhances the invasion of tumor cells, and damages the function of T cells in many ways, such as glucose deprivation, extracellular adenosine accumulation and enhanced expression of immune checkpoints (130, 132)

The reduction of TMAO in active IBD patients may reflect the depletion of TMA producing taxa caused by ecological imbalance, rather than ruling out the pathogenic role of TMAO

Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles

Integrative Medicine (Encinitas) , 2014 (reduced vs oxidized glutathione and antioxidant role)

& Hanafusa, T