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Sci Transl Med (2020) 12:eaax2220

There is no doubt that the molecular classifications have improved the prediction of the clinical outcome, and they provide key markers for a therapy tailored to the risk group

5 The annual incidence ranges from 8.8 to 23.1 per 100,000 person-years in North America, 0.624.3 per 100,000 person-years in Europe, and 7.317.4 per 100,000 person-years in Oceania, with a prevalence in adults in their 30 s and 40 s

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