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NAFLD as a continuum: from obesity to metabolic syndrome and diabetes

Downstream signaling represents the longest-lasting component of KLOW's functional presence

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We demonstrate that the cancer-related truncated variants ASXL1 1-645 and ASXL1 1-591 retain BRD4 binding function, with ASXL1 1-645 showing an enhanced ability to recruit BRD4 to ASXL1-occupied promoter regions

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