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Clin Otolaryngol 36 , 320324 (2011)

Asthma patients are susceptible to impaired respiratory mucosal immunity, and e-cigarettes further damage the immune function of the respiratory mucosa, including the functions of epithelial cells, macrophages, and neutrophils, affecting the development, severity, and acute exacerbations of asthma [71]

From indigenous tribes puffing the peace pipe to doctors prescribing cigarettes to reduce stress in the 1950s, the leaves on this magical plant have long held medicinal, recreational, ceremonial, and religious significance across multiple eras and continents