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89 (3), e13659

The cleared lysate was incubated with Glutathione Sepharose 4B (17075601, GE Healthcare) for 2 h at 4 C then washed

K., Henkel, J

The efficacy of this therapeutic combination was first validated in our breast cancer models, demonstrating that PHGDH wild type breast cancer cells do not respond to the therapeutic combination, whereas PHGDH-amplified breast cancer cells exhibited a synergistic sensitivity to suboptimal dosages of sertraline plus chloroquine (Figure S8A)