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We stated in the proposed rule that while these elements help to identify the hospital, interested parties have told us that they are inadequate to facilitate comparing hospital MRF data with other datasets that include hospital-related information and that a standard identifier would bolster these efforts

SIgAs is produced by the mother against common pathogens in her environment and is secreted into the breast milk

This represents preliminary evidence only

general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively

Ward et al., 2004