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What is increasingly emerging from the literature is that, although it is traditionally considered an extracellular pathogen, the meningococcus engages in complex interactions with host cells in the intracellular microenvironment

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Rise and Decline of the Standard Vision of Depression, Based on an Imbalance in Neurotransmitters The theory that has dominated for the past four decades considers depression to be the result of a chemical imbalance, particularly of neurotransmitters such as serotonin and norepinephrine