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Founded in 1949, Kirkman is also the oldest nutritional supplement company serving the special needs community

Melasma is a skin condition which causes brown and patchy pigmentation on the face

All mice were housed in individually ventilated cages (IVC) at standard housing conditions (22C, 14/10h light/dark cycle) with food (chow diet consisting of 18% proteins, 4.5% fibers, 4.5% fat, 6.3% ashes, Provimi Kliba SA) and water ad libitum

O'Brien S, Giles F, Talpaz M, Cortes J, Rios MB, Shan J, Thomas D, Andreeff M, Kornblau S, Faderl S, Garcia-Manero G, White K, Mallard S, Freireich E, Kantarjian HM

Heatmap representations based on the log2-transformed LFQ values of the 42 most up-regulated and the 67 most down-regulated proteins showed high reproducibility across quadruplicate experiments (Fig