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Muscle Recovery: GH/IGF-1 pathways may support protein synthesis and repair after strenuous exercise

Other Sulfonamide-containing drugs: a) Diuretics: Thiazide diuretics (e.g., Hydrochlorothiazide, Chlorthalidone) Loop diuretics (e.g., Furosemide, Bumetanide) b) Sulfonylureas (Diabetes medications): Glipizide Glyburide Glimepiride c) Carbonic Anhydrase Inhibitors: Acetazolamide (used in glaucoma, altitude sickness) Dorzolamide, Brinzolamide (ophthalmic drugs for glaucoma) d) Anticonvulsants: Zonisamide Topiramate 3

Abbreviations ALD: Alcoholic liver disease ANO1: Anoctamin-1 APAP: Acetaminophen ASCs: Adult stem cells CFTR: Cystic fibrosis transmembrane regulator COVID-19: Corona virus disease 2019 DILI: Drug-induced liver injury ESCs: Embryonic stem cells FFA: Free fatty acids GSH: Glutathione HBV: Hepatitis B virus HCV: Hepatitis C virus HEV: Hepatitis E virus HSCHep/HSC: HepaRG cells and hepatic stellate cells iPSC: Induced pluripotent stem cell IRI: Ischemia-reperfusion injury LDL: Low density lipoprotein LT: Liver transplantation NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis PHHs: Primary human hepatocytes ROS: Reactive oxygen species SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2 SHs: Small hepatocytes TNF: Tumor necrosis factor 2D: 2-Dimensional 3D: 3-dimensional References Asrani, S

We studied the impact of the mutations on the different liver cell types and assessed bile duct formation and fibrogenesis in the organoids

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