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Description

In addition, ROS induces both the activation and synthesis of AP-1, a regulator of cell growth, proliferation, and apoptosis [138, 139] and transcription factors such as STAT3, HIF-1, and p53 [118, 140, 141]

Unlike MOTS-c, which has a short half-life and requires frequent dosing, 5-amino-1MQ has a longer duration of action, allowing once-daily administration