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10.1016/j.jalz.2013.05.233 167 RizigM.Bandres-CigaS.MakariousM

Chakraborty S, Morganti C, Dey J, Zhang H, Aluri S, Gitego N, Pradhan K, Rivera B, Chutake Y, Skwarska A, Mantzaris I, Goldfinger M, Feldman EJ, Choudhary GS, Hubner S, Qiu Y, Brown BD, Verma A, Gavathiotis E, Konopleva MY, Kornblau SM , Gollob J, Ito K, Shastri A

Antagonistic glucagon receptor antibody promotes -cell proliferation and increases -cell mass in diabetic mice

To ensure a consistent 68-week comparison window, we assumed that the BMI reduction for tirzepatide did not change significantly from week 68 to week 72 based on the data provided in the clinical trials