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TOP References Hamel C, Spry C

TOc: Data curation, Writing original draft, Writing review & editing

Additionally, there is some evidence to support the use of pramipexole in patients with TRD in unipolar and bipolar depression

Inflammaging can be stimulated by a range of factors, including disordered gut microbiota, which can create a pro-inflammatory environment in the digestive tract and promote systemic inflammation

After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation