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Testing before supplementing is key

Because AOD-9604 and the incretins act through non-overlapping mechanisms (adipose lipolysis versus incretin signaling), some research protocols examine growth-hormone-fragment and incretin approaches in combination or in parallel arms which is why AOD-9604 appears as a "frequently paired" compound alongside semaglutide and tirzepatide

Woods KA, Camacho-Hbner C, Bergman RN, Barter D, Clark AJ, Savage MO

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Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function