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1 Introduction Neuroblastoma (NB) is the most common extracranial solid tumor in infants

However, the question of causality versus association still remains, and the direct/indirect mechanisms by which the acrolein adducts may lead to injury remain to be determined

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The liver, kidney, and GI tract use UDP-glucuronosyltransferase 1A9 ( UGT1A9 ) and other UGT1A superfamily enzymes for this glucuronidation process, leading to the formation of MPA 7-O-glucuronide (MPAG)