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Sam West, postdoctoral researcher12, Jadine Scragg, postdoctoral researcher12, Paul Aveyard, professor123, Jason L Oke, departmental lecturer1, Lia Willis, research assistant1, Stella J P Haffner, research assistant1, Heather Knight, research assistant1, Danni Wang, research fellow1, Sarah Morrow, clinical doctoral fellow1, Laura Heath, clinical doctoral fellow1, Susan A Jebb, professor124, Dimitrios A Koutoukidis, associate professor12 1 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK 2 National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK 3 National Institute for Health Research, Oxford Health Biomedical Centre, Warneford Hospital, Oxford, UK 4 National Institute for Health Research Applied Research Collaboration, Oxford University Hospitals NHS Foundation Trust, Oxford, UK Correspondence to: S West sam phc.ox.ac.uk (or @_WestSam on X) Accepted 6 November 2025 Abstract Objectives To quantify and compare the rate of weight regain after cessation of weight management medications (WMMs) in adults with overweight or obesity

Taken after the metabolic window closes, it offers minimal benefit, which is why timing and formulation determine outcomes

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Cross section looking east (2000 m wide) showing South32's Peake drilling and mineralized domains as well as Taylor and Clark mineralized domains (see Figure 1 for A-A' cross section line)

For pernicious anaemia or malabsorption conditions, intramuscular hydroxocobalamin injections are the standard treatment, usually given every 2-3 months after an initial loading regimen