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A postmortem MRI and histopathology study

Clinical translation potential and optimization of therapeutic strategies for PRLMs Although PRLMs have demonstrated considerable therapeutic promise in modulating inflammation and promoting tissue repair across diverse disease models, their translation into clinically viable drugs remains challenging [4]

Our study is the first to directly investigate and confirm this accumulation with aging

Science 298, 17881790

These transgene constructs permitted selective expression of the m-GPx4 or the c-GPx4 isoform by alternative mutation of the translational start sites for the individual isoforms