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After 6 months, there was a statistically significant improvement in 5 of the 8 biomarkers (HDL-C, WBC, FEV1% pred, COHb, total NNAL) in smokers who switched to HTPs compared to those who continued to smoke

For instance, increasing health consciousness and awareness of the dangers of smoking have led to a decline in smoking rates in many developed countries

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Supreme Court Justice Samuel Alito and Chief Justice John Roberts, the retirement of Justice Sandra Day O'Connor, the death of Chief Justice William Rehnquist, and the 2004 presidential election