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Second, TMAO impairs endothelial function and the production of the vasodilator nitric oxide (NO) resulting in constricted blood vessels and hypertension, another major cause of heart failure [45, 46]

Cell 175 , 17801795.e1719 (2018)

Abstract Carnitine palmitoyltransferase (CPT) II deficiency is one of the most common forms of mitochondrial fatty acid oxidation disorder

E., Bossuyt, P

Aja S, Landree LE, Kleman AM, Medghalchi SM, Vadlamudi A, McFadden JM, Aplasca A, Hyun J, Plummer E, Daniels K, Kemm M, Townsend CA, Thupari JN, Kuhajda FP, Moran TH, Ronnett GV: Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight