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A custom made MATLAB script (The Mathworks, Natick, MA, USA) was used to set a fluorescence intensity threshold for each staining

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Cadherin 23 is a component of the tip link in hair-cell stereocilia

ZNF207 increases lactate levels by upregulating LDHA expression, inducing lactylation at lysine 67 (K67 lactylation) of antioxidant protein peroxiredoxin 1 (PRDX1)

Several signaling pathways in the pathology of AD such as amyloid plaque cleavage, metal ion hypothesis, amyloid degradation, initiation of amyloidogenic and non-amyloidogenic pathway, oxidative stress hypothesis, metabolic syndrome, insulin resistance and tau phosphorylation associated, apolipoprotein (APOE)-cholesterol, neurofibrillary tangles (NFTs) accumulation and Insulin resistance prove to be beneficial in order to find the definite target for treatment of AD