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Future research should explore immune-modulatory interventions, such as leveraging the JAK/STAT pathway for neuroprotection and enhancing innate and adaptive immune clearance of toxic aggregates [176,177]

Through AKT, the binding of insulin to its receptor starts a cascade of kinase activity (Ahmed et al., 2014)

Dietary supplementation with glutamate enhanced antioxidant capacity, ammonia detoxification and ion regulation ability in Nile tilapia (Oreochromis niloticus) exposed to acute alkalinity stress

Alpha-lipoic acid-loaded nanostructured lipid carrier: sustained release and biocompatibility to HaCaT cells in vitro

Other residues from subunit-B helices D (residues 81 - 85) and E (residues 109 - 132) were also involved in ligand binding