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[38] Its important to note that weight gain or loss is not necessarily an accurate marker of metabolic health

Under normal physiological conditions, neurons can utilize glucose, lactate, or pyruvate as metabolic substrates to generate ATP through aerobic glycolysis or oxidative phosphorylation (OXPHOS)

Toxicol Pathol 27 , 618627 (1999)

Potential limitations of this study include the short duration, modest sample size, use of a home EEG headband rather than in-lab polysomnography, baseline dietary differences, lack of change on some sleep-related assessment scales, and industry involvement by the extract manufacturer

They are being studied as substances that reduce overall insulin levels in the body, which will lead to the potential restoration of normal endocrine and clinical parameters in women with PCOS