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for instance, it activates the TLR4/NF-B/miR-21 axis to downregulate RASA1 and drive tumor growth (Yang et al., 2017), and its adhesin RadD binds to CD147 to activate the PI3K-AKT-NF-B-MMP9 pathway (Wang et al., 2024) and confers resistance to 5-fluorouracil by upregulating BIRC3 through TLR4/NF-B signaling (Zhang et al., 2019)

10.1016/j.oraloncology.2018.10.018 117 TataranniT.PiccoliC

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Product Summary Epitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally developed by the St