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However, the exogenous application of glutathione improved the levels of ascorbic acid, glutathione, and nicotinamide adenine dinucleotide phosphate and the ratios of AsA/DHA, GSH/GSSG, and NADPH/NADP + (Figure 3), indicating that redox cycle activities were strengthened and that these suppressed the ROS generated by Cd toxicity

Lifestyle Factors Oxidative stress isn't just caused by what we eat

J Lumin 180:1419

Nonetheless, the role of ferroptosis in CNS diseases needs further elucidation, and currently there is no definitive evidence linking CNS diseases with ferroptosis in long-term animal model studies

Glutathione helps protect cells from oxidative stress by neutralizing free radicals and supporting healthy cellular function