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The reversible epigenetic regulation by PRC2 suggests that combining chromatin complex inhibitors with immunotherapy could overcome tumor progression associated with defective MHC-I molecules [154]

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Figure 2 CiteSpace burst detection analysis (Figure 3) further highlighted dynamic changes in research emphasis from 2015 onwards

Targeted inhibition of CTDSP1 (host gene of miR-26b) for the treatment of glioblastoma [194], brain tumors (patent number: CN113004356A), and neurodegenerative diseases (patent number: CN113004356A) was investigated at Purdue University, the University of California San Diego, the University of Texas at Austin, and Shanghai Jiao Tong University