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Their positive outcomes in preclinical models warrant further investigation, including whether these phenolic acids (or optimized derivatives) can be utilized in dietary interventions or developed into neuroprotective drugs for PD

Consequently, ncRNAs have a vital impact on the interplay of epigenetic modifications

Additional hurdles include the risk of off-target effects in mtDNA or the nuclear genome, potential immune responses to the editing machinery, and substantial technical and regulatory barriers that complicate translation of in vivo gene editing into clinical practice

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