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This selective toxicity is the key distinction from chemotherapy, which damages both healthy and cancerous tissue indiscriminately

Sci Rep 7:17366

Epstein-Barr virus and systemic autoimmune diseases

Importantly, the longevity effect of caloric restriction (CR)which is discussed in the Supplementary Section Beyond Geneticswas shown to be dependent on the proper functioning of autophagy (Jia and Levine, 2007)