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A single overdose is typically not dangerous but may cause increased nausea, vomiting, or other GI side effects

While results may take several weeks to build, the long-term benefits can be significant

however, methods such as RT-PCR for gene expression and Western blotting for protein expression were not employed

We discuss drug mechanism of action and pharmacokinetic disposition relevant to the development of peripheral neuropathy, the epidemiology and clinical presentation of chemotherapy-induced neuropathy, emerging insight into genetic susceptibilities as well as current understanding of the pathophysiology and treatment approaches

Upon entrance into the study, animals were given a 7-day acclimation period prior to any experimental procedures