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Methods: Using a combination of human CCA cells and primary tumours, we analysed the levels and function of protein SUMOylation, identifying deregulated SUMOylated proteins by immunoprecipitation and mass spectrometry analysis

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Each plan details: Additional regenerative therapies such as exosome therapy, platelet-rich plasma (PRP), growth factors, mitochondrial support peptides, and metabolic detoxification may be incorporated to optimize the treatment response