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The core gene TP53 further embodies dual effects by arresting the cell cycle (Wu et al., 2021)

They line strial blood vessels, lack fenestrations, and exhibit high levels of tight junction (TJ) proteins such as occludin, claudins, and vascular endothelial cadherin (VE-cadherin) [7]

As SARS-CoV-2 proliferates, it would result in local depletion of zinc, since many proteins (10%) and viral replication both require zinc ions

10.1038/s41598-018-19377-z 95 LiY.WangL.WangP.FanC.ZhangP.ShenJ.et al (2020)