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This raises the notion that perhaps within konzo-prone regions of sub-Saharan Africa there may be genetic variants of GPx3, or genes related to associated pathways that circulate which could alter gene expression and subsequently cause a reduction of protein abundances in these populations

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Our data revealed that the density of SYNAPTOPHYSIN1 puncta within LAMP-1 + lysosomal vesicles of IBA-1 + microglia (Fig

doi: 10.1016/j.bbagen.2013.09.017 123 MasiAFortiniPKrokidisMGRomeoEFBasciettoCDe AngelisPet al

Structural brain changes, such as reductions in prefrontal cortex and hippocampal volume, are observed in BD and major depression