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They also come with a substantial list of possible negative side effects that come with every use, including: Reduced sense of taste Bronchial spasms Burning sensation in the throat Persistent itchiness of the mouth, lips, or tongue A scratchy feeling in the lips, mouth, or throat Cough that will not go away after 1-2 weeks Dizziness that can get more severe after standing up Headache Irregular heart rate Drowsiness or sleepiness Shortness of breath or shallow breathing Difficulty breathing due to aggravation of existing conditions like asthma, emphysema, or COPD The long-term effects of vaping are still relatively unknown because the technology is still fairly emergent

An accounting of the impact of sample limitations is shown in Additional file 2

+ This self-help material was developed based on WHO Capacity Building Training Package 4 entitled Strengthening health systems for treating tobacco dependence in primary care

These results are consistent with previous research, which suggests that there exists regulatory distortions and inefficiencies in these border countries [40, 48, 49]

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