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Consideration should also be given for screening women over age 65 with a history of smoking (Derubertis et al., 2007), because about 40% of the annual deaths from AAA occur among women, in whom the disease is more deadly than men

Lobar Predilection Lower lobes are more affected due to gravity-dependent particulate deposition, leading to higher inflammation and mucus accumulation Diagnosis: Clinical: Based on symptoms of chronic cough with sputum production for 3 months/year for 2 consecutive years

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