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The authors concluded that smokers assigned to nicotine pouches smoked fewer cigarettes per day, arguing that e-cigarettes and nicotine pouches "can be a harm-reduction tool" for lower-income smokers who are "not willing to quit smoking." "There is no question that the FDA's approval of [PMI] reduced risk claim is a huge advance for smokers, because Zyn delivers nicotine in a satisfying and enjoyable manner for a microscopic fraction of the health risks of smoking," Brad Rodu, a professor of medicine at the University of Louisville and co-author of the first study of adult interest in Zyn, tells Reason