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FIGURE 3 FIGURE 4 For between-group comparisons in smokers, we observed significant brain region atrophy in the subgroup of heavy smokers compared to light smokers, mainly in GM areas of precuneus, inferior frontal gyrus, insula, STG and cerebellum anterior lob, and in WM areas of cerebellum anterior lobe ( Table 4 )

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CONFLICTS OF INTEREST The authors have each completed and submitted an ICMJE form for disclosure of potential conflicts of interest