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This approach is especially useful for individuals with high toxic loads or chronic exposure to pollutants

34 A relative deficiency of anti-proteases, such as 1-antitrypsin, because of their inactivation by oxidants from cigarette smoke or released from inflammatory leucocytes, causes a protease/anti-protease imbalance in the lungs

These data suggest that the TCA cycle is likely partially blocked downstream of complex II in cKOt mice

Notably, ZIP1 deficiency-mediated Zn homeostasis dysregulation in prostate cancer cells alters cellular energetics and apoptotic pathways, promoting tumor growth (Figure 5A)

A better understanding of the pathophysiological mechanism and the correlation between the alcohol intake, the biological markers, and oxidative stress, is an important issue for the better management of ALD