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To better understand the non-nicotine constituents in this study, the nicotine content of the cut tobacco in the experimental cigarettes was reduced to 0.7 mg/g, which was 2.8% of the 3R4F standard cigarette level (Figure 1B), and was close to 0.40.6 mg/g ( Despite significant inhibition of MAOA activity (Figures 5C,D), individual non-nicotine constituents caused no DA increase (Figures 3DF)

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