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Myelodysplastic syndrome is a group of diseases in which the bone marrow doesnt make enough healthy blood cells

Deletion of Nrf2 abrogated the protective effects of AZI in vitro and in vivo To further confirm the role of Nrf2 in AZI-ameliorating airway epithelial barrier dysfunction, lentiviral-delivered shRNAs was used to knock down Nrf2 expression in HBECs