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Smoking is one of the most preventable causes of disease and death worldwide. It affects nearly every organ in the body through mechanisms such as chronic inflammation, oxidative stress, endothelial dysfunction, and Smoking and its effects on the skin The Many Dangers of Tobacco Use UC Davis Biotechnology Program Dysregulation of immunity by cigarette smoking promotes inflammation and cancer: A review ScienceDirect Heated tobacco and cigarettes cause the same gut and vascular damage, study finds

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