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Because many e-liquids contain nicotine, which is well known for its powerful addictive properties [41], e-cigarette users can easily switch to conventional cigarette smoking, avoiding smoking cessation

Nicotine causes blood vessels to constrict, when this happens it is possible for blood clots to form affecting blood flow to the capillaries

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Chemicals such as carbon monoxide and cyanide in tobacco smoke reduce the elasticity of alveoli so the lungs can no longer fully exhale air

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