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So when were talking about loss of life expectancy, life expectancy would tend to be lived in relatively good health. The research, which was commissioned by the UK Department for Health and Social Care, includes mortality data on men from the British Doctors Study and data on women from the Million Women Study

[13] They moved to Santa Monica, California, in 1954, and then to Los Angeles in 1958

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Moreover, microstructural studies found that the generally higher fractional anisotropy (FA) seen in smokers may reflect an increase in FA that follows the initiation of smoking, but prolonged smoking appears to reverse this effect with a progressive decline in FA with increasing pack-years of smoking 34, 35