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PRKN can be modulated via protein kinase A (PKA)-p38-cAMP response element-binding protein (CREB), deubiquitination by ubiquitin-specific protease 33 (USP33), and microRNA regulation such as miR-218 34

Beyond vitamin D (VD) effect on bone homeostasis, numerous physiological functions in human health have been described for this versatile prohormone

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