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The data table additionally provides details regarding the comparison group, smoking habits (if assessed), the pharmaceutical molecule studied, a description of the intervention and its outcomes, the postulated pharmacokinetic and pharmacodynamic mechanisms, the enzymes involved in the metabolism of drugs and affected by smoking, studied in each included article and the major findings for each study included

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Questions about the origin of the rebound in cigarette sales It is not yet clear whether this increase in sales is due to new consumers, returning smokers, or increased sales volumes among existing smokers

Materials and methods Analytical framework and study design This study employed a cross-sectional, video-based content analysis approach using thematic analysis to examine physicians perspectives on e-cigarettes as presented in YouTube videos