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Including fibroblasts or other mesenchymal cell populations in co-culture models could be crucial for studying smoke-induced effects, as these cells contribute to extracellular matrix remodeling, fibrosis, and epithelial-mesenchymal interactions, which are key processes in COPD and emphysema progression

For them, nicotines stimulant properties need to be handled with more care, which makes getting a doctors advice before starting absolutely essential

State and local action to prohibit the sale of menthol cigarettes and all other tobacco products remains critical and can save lives and prevent addiction now

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