Meta-analyses and large cohort studies consistently report that smoking is associated with worse clinical outcomes among infected individuals, although interpretation is limited by residual confounding, smoking misclassification, and selection bias ( Evidence regarding infection risk is more heterogeneous, and the so-called smoking paradox remains controversial
Ive seen this happen quite a few times
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The most common reported effect of smoking tobacco alongside cannabis is an intensification of the high, although some report that tobacco use actually has the opposite effect and reduces the high
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