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Polyphyllin B restored microbial balance, inhibited STAT3/NCOA4 signaling, and ameliorated lung injury by enhancing ferritin and LC3 expression and mitigating mitochondrial damage, highlighting its therapeutic potential in smoking-related lung disease [108]

A phylogenetic tree was constructed from the sequences, and the significant differences in the amplicon sequence variants were determined

Polonium-210 in cigarette smokers

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Limitations of the current research include the small number of studies, the small sample size, the evaluation mostly of first-generation devices, the limited investigation on which characteristics of the device and patterns of use (e.g., wattage, temperature) could be major contributors of exposure, and the evaluation of devices that are selected by the investigators but which do not necessarily reflect what the consumers are using